Gangs
| Gang | Description |
|---|---|
| Maelstrom | Known for brutality and cyberpsychosis. |
| Valentinos | Latino gang rooted in tradition and honor. |
| 6th Street | Formed by ex-military patriots. |
| Voodoo Boys | Haitian netrunners based in Pacifica. |
| Animals | Enhanced brawlers who reject cyberware. |
| Tyger Claws | Japanese gang with ties to Yakuza. |
| The Mox | Formed by sex workers to protect themselves. |
| Scavengers | Ruthless organ and cyberware harvesters. |
| Wraiths | Nomad outcasts (Raffen Shiv) who raid. |
| Aldecaldos | Nomadic family-oriented group. |
| Barghest | Paramilitary gang in Dogtown, led by Kurt Hansen |
Megacorporations
| Corporation | Description |
|---|---|
| Arasaka | Japanese megacorp specializing in security. |
| Militech | American weapons manufacturer. |
| Kang Tao | Chinese firm focused on Smart weapons. |
| Biotechnica | Develops synthetic food and biofuels. |
| Petrochem | Energy giant producing CHOOH2 fuel. |
| Zetatech | Cyberware and robotics manufacturer. |
| Tsunami Defense Systems | Weapons developer. |
| Kiroshi Opticals | Makers of the iconic Kiroshi cyberoptics. |
| Night Corp | Manages Night City infrastructure. |
| Trauma Team | Elite paramedical response unit. |
Other
| Faction | Description |
|---|---|
| NCPD | Night City Police Department. |
| NetWatch | Government-backed group. |
| Netrunners | Freelance hackers. |
| Mercs | Independent contractors. |
| Nomads | Tribal groups living outside the city. |